Journal of Molecular Biology, Cover Design, Volume 434 Issue 5, March 2022
Building Structural Models of a Whole Mycoplasma Cell
Cover Illustration: Building and visualizing whole cell models has been a long-standing cross-disciplinary challenge for the research community. The confluence of data accessibility and advances in computational resources have opened the door to structural investigations of entire cells. A 3D model of an entire Mycoplasma genitalium (MG) has been built and visualized through CellPACK. This model recapitulates the data from the whole-cell system biology simulations and provides a structural representation for all MG proteins, DNA and RNA molecules. The cover incorporates both the 3D whole-cell bacterial model and the gene expression data resulted from the system biology simulations. Illustration by Martina Maritan.
Reference: https://www.sciencedirect.com/science/article/abs/pii/S002228362100588X
